Pharmaceutical heterocyclic compounds and compositions
US4281008A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 6, 1980 |
| Grant date | Jul 28, 1981 |
| Priority date | — |
| Expiry date | Mar 6, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D303/26
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The compounds of the formula: ##STR1## wherein: R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.7, which may be the same or different, each represent hydrogen, hydroxy, alkyl or alkoxy of 1 to 6 carbon atoms, amino, acyl or acylamino of 2 to 6 carbon atoms, alkenyl of 2 to 6 carbon atoms, halogen, or alkoxy of 1 to 6 carbon atoms substituted by phenyl, PA0 X is a hydrocarbon chain of 1 to 10 carbon atoms optionally substituted by a hydroxy group, PA0 A is oxygen or is absent, PA0 Q represents a straight or branched alkylene, alkenylene or alkynylene group of 2 to 6 carbon atoms, and PA0 D represents carboxy, 5-tetrazolyl or carboxamido-5-tetrazolyl, PA0 and pharmaceutically acceptable salts, esters and amides thereof, PA0 are pharmaceutically active, being antagonists of the slow reacting substance of anaphylaxis (SRS-A) or its pathological effects. Pharmaceutical compositions containing the compounds are also described, as well as processes for preparing the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.