Patent · US Expired

3-Piperidino or apiperazino-1-phenyl or 1-substituted phenyl isoquinoline and antidepressant compositions thereof

US4282222A · kind A · utility

6Cited by

2References

5Claims

0Family size

Assignee

Hoechst GmbH · DE

Inventors

Wilhelm Bartmann
Elmar Konz · Kelkheim, DE
Harry M. Geyer · Flemington, US

Key dates

Filing date	Sep 12, 1979
Grant date	Aug 4, 1981
Priority date	—
Expiry date	Sep 12, 1999

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/26
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Isoquinolines of the formula ##STR1## in which R.sub.1 is piperidino, piperazino or piperazino N-substituted thereof by alkyl of 1 to 4 carbon atoms, alkylene of 1 to 4 carbon atoms wherein said alkylene is substituted in turn by fluorobenzoyl, or CHO; R.sub.2 is phenyl or phenyl substituted by alkyl of 1 to 4 carbon atoms, halogen, amino or nitro; and R.sub.3 is hydrogen or halogen, a process for their preparation and medicaments containing the isoquinolines, especially the use of said medicaments as antidepressants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.