Patent · US Expired

Thiopropionamides, and the pharmaceutical compositions

US4283407A · kind A · utility

4Cited by
1References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 25, 1978
Grant dateAug 11, 1981
Priority date
Expiry dateSep 25, 1998

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D279/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to omega-mercaptopropionylamides, the nitrogen atom of which is included as a ring atom of a cyclic amino acid. The application also discloses a process for producing said compounds which comprises reacting an omega-mercaptopropionic acid, or a functional derivative thereof, with a cyclic amino acid. This invention further relates to pharmaceutical compositions incorporating such an omega-mercaptopropionylamide as active ingredient together with a pharmaceutically-acceptable carrier or vehicle, and a method of employing said compounds. They find a use in human therapy, namely, as antihypertensive agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.