Process for preparing 3-carbamoyloxymethyl cephalosporins
US4284767A · kind A · utility
1Cited by
4References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 15, 1980 |
| Grant date | Aug 18, 1981 |
| Priority date | — |
| Expiry date | Jan 15, 2000 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the preparation of a 3-carbamoyloxymethyl cephalosporin compound which comprises reacting a 3-hydroxymethyl cephalosporin with dihalophosphinyl isocyanate and converting the resulting 3-phosphonocarbamoyloxymethyl cephalosporin reaction product by hydrolysis to the desired compound. The isocyanates used in the process are readily available and easy to handle and thus the process avoids the use of hazardous and/or expensive reagents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.