4-Arylpiperidine derivatives
US4286095A · kind A · utility
1Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 1, 1979 |
| Grant date | Aug 25, 1981 |
| Priority date | — |
| Expiry date | May 1, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/54
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A 4-phenyl piperidine having the formula: ##STR1## wherein R.sub.1 is a straight chain lower alkyl group; R.sub.2 is --COCH.sub.3, --COC.sub.2 H.sub.5 or ##STR2## R.sub.3 is --OCOCH.sub.3, --OCOC.sub.2 H.sub.5, --OCO -cycloalkyl, or --OCOC.sub.6 H.sub.4 --Z; wherein Z is hydrogen, lower alkyl, lower alkoxy or chlorine, and X is oxygen: or an addition salt thereof with a pharmaceutically acceptable organic acid or inorganic acid. The compounds have have found to have, inter alia, stimulatory effects on the central nervous system which is indicative of their use as antidepressants in humans.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.