Vascular prosthesis and method of making the same
US4286341A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 23, 1979 |
| Grant date | Sep 1, 1981 |
| Priority date | — |
| Expiry date | May 23, 1999 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2250/0023
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A vascular prosthesis and its method of fabrication. The prosthesis takes the form of a flexible and conformable support tube having a luminal surface formed of a smooth, homogenous, and substantially non-thrombogenic hydrogel having relatively small pores or microvoids suitable for tissue ingrowth but resistant to thrombus formation, and having an outer surface formed of essentially the same hydrogel having a heterogenous microstructure which includes relatively large pores or macrovoids especially suitable for cellular ingrowth from perigraft sources and attachment sites. In one embodiment, the tubular substrate is foraminous and the inner and outer hydrogel layers merge through the interstices of the substrate to provide a unified ground substance characterized by strata having selectively different pore characteristics for promoting effective endothelialization and for reducing possibilities of thrombotic occlusion.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.