Patent · US Expired

Process for preparing 2-chlorosulfinylazetidinones

US4289695A · kind A · utility

9Cited by
3References
16Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJun 18, 1979
Grant dateSep 15, 1981
Priority date
Expiry dateJun 18, 1999

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02P20/55
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Improved process for converting a penicillin sulfoxide ester to a 2-chlorosulfinylazetidin-4-one intermediate which on cyclization affords a 3-exomethylenecepham sulfoxide, wherein the penicillin sulfoxide ester is reacted with an N-chloro halogenating agent in the presence of a cross-linked polyvinylpyridine polymer to provide the 2-chlorosulfinylazetidin-4-one.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.