2-Benzoyl-4-nitroanilides and their use as medicaments
US4289770A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 13, 1980 |
| Grant date | Sep 15, 1981 |
| Priority date | — |
| Expiry date | Jun 13, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/15
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New derivatives of 2-benzoyl-4-nitro anilides, their preparation and their use as medicaments. The new chemical derivatives of the invention have the general formula ##STR1## in which R represents a linear or branched alkyl group, an alkenyl group, a cycloalkyl group or a benzyl group, PA0 R.sub.1 represents a hydrogen atom, an alkyl group or a hydroxy alkyl group, PA0 R.sub.2 represents a hydroxy-alkyl, alkenyl or alkynyl group, possibly substituted one or more times by an alkyl radical, or a cycloalkyl group having three to six carbon atoms; PA0 R.sub.1 and R.sub.2 may furthermore form, with the nitrogen atom to which they are attached, a nitrogen heterocycle containing possibly a second heteroatom selected from among oxygen and nitrogen; PA0 under the condition, however, that when R.sub.2 represents a hydroxy-alkyl group R.sub.1 may not be a hydrogen atom. Use as hypnotic agents for the treatment of insomnia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.