Novel hydrocortisone derivative
US4290962A · kind A · utility
31Cited by
4References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 26, 1979 |
| Grant date | Sep 22, 1981 |
| Priority date | — |
| Expiry date | Mar 26, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J5/0053
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
17.alpha.-butyryloxy-11.beta.-hydroxy-21-propionyloxy-4-pregnen-3,20-dione, i.e., hydrocortisone 17-butyrate 21-propionate of the present invention is prepared by acylating hydrocortisone 17-butyrate with propionic acid anhydride or halide. The compound of the present invention has excellent anti-inflammatory effect, percutaneous absorption and less side effect.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.