Treatment of animals exposed to or subject to exposure to organophosphate animal poisonous nerve agents
US4292308A · kind A · utility
1Cited by
2References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 21, 1979 |
| Grant date | Sep 29, 1981 |
| Priority date | — |
| Expiry date | Aug 21, 1999 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/163333
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method is provided for treatment of animals exposed to or subject to exposure to organophosphate animal poisonous nerve agents. The animals are injected with an effective amount of modified neurotoxin, preferably intramuscularly or intravenously, either prior to or shortly after exposure to the nerve agents. Particularly when the injection is administered prior to exposure, and where the dosage is of a higher amount, certain compositions achieve 100% survivors of Rhesus monkeys, even in the face of a challenge of 5 LD.sub.50 of the nerve agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.