Alkylation of nitriles using an electrogenerated base and an alkylating agent
US4293392A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 17, 1980 |
| Grant date | Oct 6, 1981 |
| Priority date | — |
| Expiry date | Jan 17, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC25B3/29
- WIPO fieldSurface technology, coating
- WIPO sectorChemistry
Abstract
The invention is a process for alkylating nitriles using an electrogenerated base and an alkylating agent comprising (a) electro-reducing an azobenzene probase at a cathode in an electrolysis medium comprising the azobenzene probase, a nitrile and a supporting electrolyte to produce an electrogenerated base, (b) deprotonating the nitrile with the electrogenerated base to produce a nitrile anion, and (c) reacting the nitrile anion with alkylating agent to form alkylated nitrile; the probase being more easily electro-reducible than the nitrile and producing an electrogenerated base strong enough to deprotonate the nitrile which is sufficiently acidic to permit such deprotonation, and the electrogenerated base not reacting readily, unless rapidly reversibly, with the alkylating agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.