Analgesic 2-(2-alkoxy-ethyl)-2'-hydroxy-6,7-benzomorphans and salts thereof

US4293556A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Herbert Merz · Ingelheim am Rhein, DE
• Klaus Stockhaus

Key dates

• Filing date: May 28, 1980
• Grant date: Oct 6, 1981
• Expiry date: May 28, 2000

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## wherein R.sub.1 is methyl, ethyl or propyl; PA1 R.sub.2 is hydrogen, methyl or ethyl; and PA1 R.sub.3 is ##STR2## where R.sub.4 is hydrogen or methyl, PA3 R.sub.5 is methyl, ethyl or propyl, and PA3 n is 1 or 2, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as the salts are useful as analgesics.