20-O-Acylmaytansinoids
US4294757A · kind A · utility
287Cited by
6References
37Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 15, 1980 |
| Grant date | Oct 13, 1981 |
| Priority date | — |
| Expiry date | Jan 15, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/188
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel 20-demethoxy-20-acyloxymaytansinoids representable by the formula: ##STR1## [wherein X is chlorine or hydrogen; R.sub.1 is hydrogen or acyl group; R.sub.2 is acyl group] are produced from 20-demethoxy-20-hydroxymaytansinoids by means of acylation. The compounds are useful as antifungal, antiprotozoal or antitumor agent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.