Substituted 4-hydroxy-isophthalic acid picolylamides having a pharmaceutical activity in thromboembolic disorders
US4294833A · kind A · utility
4Cited by
2References
24Claims
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Key dates
| Filing date | Aug 29, 1978 |
| Grant date | Oct 13, 1981 |
| Priority date | — |
| Expiry date | Aug 29, 1998 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There are prepared 4-hydroxy-isophthalic acid bis (3- or 4-picolyl-amides) of the formula (I) ##STR1## where R' is H or an aliphatic or alicyclic hydrocarbon group with 1 to 16 carbon atoms, R'''' is 3-pyridyl or 4-pyridyl, R''' is H, Cl, NO.sub.2, or --OCH.sub.3, R'' is an aliphatic or alicyclic hydrocarbon group with 1 to 8 carbon atoms with the exception that when R'''' is 3-pyridyl and R' and R''' are both H, then R'' is an aliphatic or alicyclic hydrocarbon radical with 3 to 8 carbon atoms. The compounds are useful in inhibition of blood platelet aggregation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.