Certain heterocyclic sulfoximide derivatives

US4294838A · kind A · utility

Inventors

• Peter Stoss · Illertissen, DE
• Gerhard Satzinger · Denzlingen, DE
• Manfred Herrmann
• Wolfgang Heldt

Key dates

• Filing date: May 15, 1980
• Grant date: Oct 13, 1981
• Expiry date: May 15, 2000

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D333/34
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Sulphoximide derivatives of the general formula: ##STR1## wherein R.sub.1 is a phenyl, thienyl, furyl or pyridyl ring; R.sub.2 is a thienyl, furyl, or pyridyl ring; R.sub.3 and R.sub.4 are the same or are different and are alkyl groups containing up to 6 carbon atoms or together with the nitrogen atom to which they are attached form a pyrrolidine, piperidine, or morpholine ring; and n is a whole number from 1 to 5; and the pharmaceutically acceptable organic and inorganic acid addition and quaternary ammoniuim salts thereof. The compounds of the invention exhibit anti-bronchospasmolytic activity.