3,4-Dihydro-3-oxopyrido[2,3-b]-pyrazines, compositions and use thereof
US4296114A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 2, 1979 |
| Grant date | Oct 20, 1981 |
| Priority date | — |
| Expiry date | Aug 2, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D241/44
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
There are described compounds of formula I, ##STR1## in which R.sub.1 is phenyl substituted by halogen, alkoxy, alkyl, carboxy-alkyl, --NR.sub.4 R.sub.5, carboxy or alkoxy carbonyl, PA0 R.sub.3 is hydrogen, alkyl, mono- or di-carboxy alkyl, halo, alkoxy, phenyl, halo-phenyl, hydroxy, phenoxy, thiol, thioalkoxy, thiophenoxy, --NR.sub.4 R.sub.5, cyano, --COOH, carboxyureido, --CF.sub.3, --COR.sub.6, hydroxyalkyl, aminoalkyl, or alkoxy substituted by NR.sub.4 R.sub.5, PA0 ring A is a benzene or a pyridine ring which optionally carries up to 4 substituents R.sub.3, which may be the same or different, PA0 R.sub.4 and R.sub.5, which may be the same or different, each represent hydrogen, phenyl, halophenyl or alkyl, the alkyl optionally being substituted by alkoxy or by a mono- or di-alkyl or unsubstituted amino group; or R.sub.4 and R.sub.5, together with the nitrogen atom to which they are attached, form a piperidine, morpholine or an optionally alkyl substituted piperazine ring, and PA0 R.sub.6 is hydrogen or alkyl, PA0 provided that (i) when R.sub.1 is phenyl substituted by chlorine or bromine, ring A is not a benzene ring substituted by chlorine or bromine, or (ii) when R.sub.1 is ph…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.