3-Aryloxy-3-aryl-propaneamines and their method of use
US4296126A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 22, 1979 |
| Grant date | Oct 20, 1981 |
| Priority date | — |
| Expiry date | Feb 22, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C233/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel benzene-propanamines of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, chlorine, fluorine and bromine, R.sub.1 is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms, R.sub.2 is alkyl of 1 to 5 carbon atoms, R.sub.3 is selected from the group consisting of hydrogen, chlorine, bromine, --CF.sub.3, methyl and methoxy when R.sub.4 is nitro and R.sub.3 is selected from the group consisting of amino and acetamido when R.sub.4 is hydrogen and their non-toxic, pharmaceutically acceptable acid addition salts having anorexigenic activity and inhibit serotonine uptake in vivo and in vitro and their preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.