Method of manufacture and use of improved 2.beta., 16.beta.-piperidino androstanes
US4297351A · kind A · utility
7Cited by
5References
44Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 7, 1980 |
| Grant date | Oct 27, 1981 |
| Priority date | — |
| Expiry date | Oct 7, 2000 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
New and pharmacologically useful pharmaceutically acceptable acid addition salts are disclosed for the 16.beta.-monoquaternary ammonium derivatives of either the 2.beta., 16.beta.-bis-piperdino-3.alpha., 17.beta.-dihydroxy-5.alpha.-androstane 3.alpha., 17.beta.-di-lower aliphatic esters or the 2.beta., 16.beta.-bis-piperidino-3.alpha.-hydroxy-5.alpha.-androstane-3.alpha.-lowe r aliphatic esters, which salts are surprisingly relatively stable in aqueous solutions, so that they provide stable aqueous injection preparations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.