Hydantoin derivatives
US4298745A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 19, 1979 |
| Grant date | Nov 3, 1981 |
| Priority date | — |
| Expiry date | Nov 19, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/76
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula 1: ##STR1## wherein: X is O or S; PA1 R.sub.1 is hydrogen, or CO.sub.2 R.sub.1 represents an ester group in which the R.sub.1 moiety contains from 1-12 carbon atoms; PA1 R.sub.2 is hydrogen or C.sub.1-4 alkyl; PA1 R.sub.4 is C.sub.1-9 alkyl, C.sub.3-8 cycloalkyl or C.sub.3-8 cycloalkyl-C.sub.1-6 alkyl; or PA1 R.sub.2 and R.sub.4 taken with the carbon atom to which they are joined represent a C.sub.5-8 cycloalkyl group; and PA1 R.sub.5 is C.sub.1-6 alkyl; and salts thereof, having similar activity to natural prostaglandins, a process for their preparation, intermediates useful in that process and pharmaceutical compositions containing them.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.