Patent · US Expired

Novel polypeptides having thymic activity or an antagonistic activity and processes for their synthesis

US4301065A · kind A · utility

8Cited by
5References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 24, 1978
Grant dateNov 17, 1981
Priority date
Expiry dateMay 24, 1998

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S930/18
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention is concerned with novel polypeptides and processes for the synthesis thereof. It is concerned with compounds having the sequence EQU X-Gln-Gly-Gly-Y in which Y represents -Ser-Asn and X represents Ser-, Lys-Ser-, Ala-Lys-Ser-, Glx-Ala-Lys-Ser-; Glx representing Pyro-Glu or Gln; and when X represents Glx-Ala-Lys-Ser-, Y may in addition represent -Ser; as well as their derivatives comprising one or two modified amino acids, with the exception of the unmodified compound PyroGlu-Ala-Lys-Ser-Gln-Gly-Ser-Asn. These polypeptides are useful as medicines.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.