Heparin preparation
US4301153A · kind A · utility
43Cited by
3References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 30, 1978 |
| Grant date | Nov 17, 1981 |
| Priority date | — |
| Expiry date | Mar 30, 1998 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0075
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A heparin preparation which exhibits elevated anticoagulant activity and a process for producing the preparation. Conventional heparin exhibiting characteristic anticoagulant activity and molecular heterogeneity is incubated with antithrombin-heparin cofactor extracted from plasma. A portion of the heparin forms a complex with the cofactor. The uncomplexed heparin fraction is then separated from the complexed fraction, and the complexed fraction is broken down to produce cofactor and an active form of heparin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.