Patent · US Expired

3-Deamino-3-(4-morpholinyl) derivatives of daunorubicin and doxorubicin

US4301277A · kind A · utility

11Cited by
2References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 20, 1980
Grant dateNov 17, 1981
Priority date—
Expiry dateOct 20, 2000

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H15/252
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Described are 3'-deamino-3'-(4-morpholinyl) derivatives of daunorubicin and doxorubicin having the formula ##STR1## wherein R is COCH.sub.3 or --CHOHCH.sub.3 in the case of daunorubicin derivatives, or is --COCH.sub.2 OH or --CHOHCH.sub.2 OH in the case of doxorubicin derivatives together with their pharmaceutically acceptable acid addition salts. The compounds have utility as antitumor agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.