4-Phenoxy-phenoxy-alkane-carboxylic acid derivatives and process for their manufacture

US4301295A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Helmut Nahm · Kelkheim, DE
• Ernold Granzer · Kelkheim, DE

Key dates

• Filing date: Aug 20, 1980
• Grant date: Nov 17, 1981
• Expiry date: Aug 20, 2000

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C51/09
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel 4-phenoxy-phenoxy-alkane-carboxylic acid derivatives of the formula I ##STR1## in which R.sub.1 stands for hydrogen, methylthio, cyclopentyl, cyclohexyl, phenyl, methylcyclohexyl, ethylcyclohexyl, or R.sub.1 and R.sub.3 together stand for a --CH.dbd.CH--CH.dbd.CH-- bridge or--unless at least one of the substituents R.sub.2 to R.sub.8 stands for hydrogen, or if R.sub.9 stands for a radical having at least 2 carbon atoms--for chlorine, PA1 R.sub.2 and R.sub.3, independent of one another, each stands for hydrogen, chlorine or alkyl of 1 to 4 carbon atoms, PA1 R.sub.4 stands for hydrogen, chlorine, alkyl of 1 to 4 carbon atoms, cyclopentyl, cyclohexyl, methylcyclohexyl or R.sub.3 and R.sub.4 together stand for a --CH.dbd.CH--CH.dbd.CH-- bridge, PA1 R.sub.5, R.sub.6 and R.sub.7, independent of one another, each stands for hydrogen or alkyl of 1 to 4 carbon atoms, PA1 R.sub.8 stands for hydrogen, alkyl of 1 to 4 carbon atoms or allyl, PA1 R.sub.9 stands for alkyl of 1 to 10 carbon atoms or phenyl and PA1 X stands for hydrogen, the cation of a physiologically acceptable inorganic or organic base of a hydrocarbon radical of 1 to 10 carbon atoms, having a strong action on the lipide a…