Patent · US Expired

Liposome carriers in leishmaniasis chemotherapy with 8-aminoquinoline derivatives

US4302459A · kind A · utility

21Cited by

2References

17Claims

0Family size

Assignee

The United States of America as represented by the Secretary of the Army · US

Inventors

Edgar A. Steck · Silver Spring, US
Carl R. Alving · Bethesda, US

Key dates

Filing date	Mar 19, 1980
Grant date	Nov 24, 1981
Priority date	—
Expiry date	Mar 19, 2000

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An improved method is provided for the chemotherapy of leishmanial infects. An 8-aminoquinoline anti-leishmanial agent is encapsulated within liposomes and the liposome-encapsulated drug is injected into the body. Subject use of a liposome carrier has produced marked enhancement of the effectiveness of the drug against leishmanial parasites in the liver (such as characteristic of infections which are difficult to treat).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.