Therapeutically active, substituted piperidines and pyrrolidines therapeutic compositions thereof and methods of use thereof
US4302465A · kind A · utility
44Cited by
3References
23Claims
0Family size
Inventors
Key dates
| Filing date | Nov 26, 1979 |
| Grant date | Nov 24, 1981 |
| Priority date | — |
| Expiry date | Nov 26, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/62
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of formula ##STR1## in which m and n are a pair of integers such that m=0 or 1 and n=3-m or m=0, 1 or 2 and n=4-m, R is straight or branched C.sub.2 to C.sub.4 alkyl having a terminal hydroxy group, PA1 R.sub.1 is methyl or methoxy, PA1 R.sub.2 is methyl or ethyl and PA1 R.sub.3 is hydrogen or methyl; or a pharmaceutically acceptable salt thereof is provided, as well as compositions containing these compounds and processes for preparing them. The compounds can be used to produce topical and local anaesthetic effects in mammals and are also useful as heart anti-arrhythmic agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.