3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
US4304915A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jul 3, 1979 |
| Grant date | Dec 8, 1981 |
| Priority date | — |
| Expiry date | Jul 3, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The compounds of formula I ##STR1## wherein R.sub.1 is hydrogen or methyl, PA1 R.sub.3 is hydrogen, methyl, hydroxymethyl, carboxyl, alkoxycarbonyl of 2 to 5 carbon atoms, carbamoyl or cyano and PA1 R.sub.2 is a group (a) to (i), groups (a) to (i) having the following significances: ##STR2## wherein n is 0 or 1 and R.sub.a, R.sub.b, R.sub.c and R.sub.d independently are hydrogen or alkyl of 1 to 4 carbon atoms; ##STR3## wherein R.sub.e is hydrogen or alkyl of 1 to 4 carbon atoms; ##STR4## wherein R.sub.h is halogen of atomic number of from 9 to 35; ##STR5## wherein R.sub.i together with R.sub.n is o-phenylene optionally substituted by alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms or halogen of atomic number of from 9 to 35 and, PA2 when R.sub.3 is cyano, PA2 R.sub.i together with R.sub.n additionally is lower alkylene separating by 2 or 3 carbon atoms the nitrogen atom to which R.sub.i is bound from the nitrogen atom to which R.sub.n is bound and PA2 R.sub.m is hydrogen or an aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, araliphatic or aromatic moiety or an acyl moiety, with the provisos that, PA1 (A) when R.sub.1 is hydrogen and R.sub.2 is a group (b), R.sub.3…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.