Demethyl maytansinoids
US4307016A · kind A · utility
292Cited by
3References
53Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 27, 1980 |
| Grant date | Dec 22, 1981 |
| Priority date | — |
| Expiry date | May 27, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/585
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel demethylmaytansinoids representable by the formula: ##STR1## [wherein X is Cl or H; R.sub.1 is H or acyl group] are produced from maytansinoids by means of enzymic transformation. The demethylmaytansinoids are useful as antifungal, antiprotozoal or antitumor agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.