1.alpha., 25-dihydroxy-2.beta.-fluorovitamin D.sub.3
US4307025A · kind A · utility
7Cited by
1References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 17, 1981 |
| Grant date | Dec 22, 1981 |
| Priority date | — |
| Expiry date | Feb 17, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/62
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides new derivatives of vitamin D.sub.3, specifically, 1.alpha.,25-dihydroxy-2.beta.-fluorocholecalciferol. The compound is characterized by vitamin D-like activity as measured by its ability to stimulate intestinal calcium transport, mobilization of calcium from bone, increase serum inorganic phosphorous and in their antirachitic activity. The compound, could, therefore, find ready application as a substitute for vitamin D in its various known applications and in the treatment of various metabolic bone diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.