Anorexigenic 4-[(3,4-dialkoxyphenyl)alkyl]-2-imidazolidinone derivatives
US4308278A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 1, 1979 |
| Grant date | Dec 29, 1981 |
| Priority date | — |
| Expiry date | Nov 1, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/78
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
4-[(3,4-Dialkoxyphenyl)alkyl]-2-imidazolidinone derivatives having the formula I ##STR1## wherein R.sup.1 stands for a cycloalkyl group containing from 3 to 6 carbon atoms or benzyl group; PA0 R.sup.2 stands for hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms; PA0 R.sup.3 stands for hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms; PA0 R.sup.4 stands for hydrogen atom, or an alkyl group containing from 1 to 4 carbon atoms or an alkoxycarbonyl group containing from 1 to 4 carbon atoms; and PA0 R.sup.5 stands for hydrogen atom or an alkoxycarbonyl group containing from 1 to 4 carbon atoms, are prepared by PA0 (a) reducing a hydantoin derivative having the general formula II, wherein R.sup.1 and R.sup.2 are as defined above, with lithium aluminum hydride in a neutral organic solvent, or PA0 (b) hydrogenating catalytically an 1,3-dihydro-2H-imidazol-2-one derivative having the general formula III, wherein R.sup.1 and R.sup.3 are as defined above, while the meaning of R.sup.4 is hydrogen atom or an alkyl group containing from 1 to 4 carbon atoms, or PA0 (c) reacting a carbamate derivative having the general formula IV, wherein R.sup.1 is as defined…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.