Pyrrolo-benzodiazepine compounds and anti-tumor composition thereof
US4309437A · kind A · utility
81Cited by
2References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 4, 1980 |
| Grant date | Jan 5, 1982 |
| Priority date | — |
| Expiry date | Mar 4, 2000 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel 5,10,11,11a-tetrahydro-8-methyl-11-sulfo or sulfino-1H-pyrrolo[2,1-c][1,4]-benzodiazepin-2-acrylamides which have antitumor activity and low toxicity are prepared by reacting corresponding 11-reactive compound with a reactive sulfur compound to form 11-sulfino compounds and, if desired, oxidizing the 11-sulfino compounds to obtain 11-sulfo compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.