Implantable bone replacement materials based on calcium phosphate ceramic material in a matrix and process for the production thereof

US4309488A · kind A · utility

Assignee

• Battelle Institute e.V. · DE

Inventors

• Helmut Heide · Kelkheim, DE
• Eva Poeschel · Bad Soden, DE
• Ulrich Roth · Darmstadt, DE

Key dates

• Filing date: Jun 21, 1979
• Grant date: Jan 5, 1982
• Expiry date: Jun 21, 1999

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/12021
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

An implantable bone replacement material (body) based on completely or partially resorbable particles incorporated in a matrix material. The particles are composed of bioactive sintered calcium phosphate ceramic material having a CaO:P.sub.2 O.sub.5 composition ratio between 3:1 and 4:1. The replacement material (body) consists of a metal containing calcium phosphate ceramic material in the form of a monolayer of particles in the peripheral areas of the material (body) which serve as interfaces to the body tissue. The metal is compatible with body tissue. The ceramic particles have a size range between about 500 .mu.m and a few millimeters. The calcium phosphate particles are located so that they lie exposed on the upper surface of the material (body). Other embodiments and processes are also disclosed.