Monoradioiodinated imidazole derivatives
US4310675A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 24, 1979 |
| Grant date | Jan 12, 1982 |
| Priority date | — |
| Expiry date | May 24, 1999 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/60
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Monoradioiodinated derivatives of compounds employed in a radioassay prepared from precursors which are either active esters, amino acids, or amines, including a phenolic of imidazole substituent group in which one of the possible two sites on the group for radioiodination is substituted to permit production of a monoradioiodinated derivative. A preferred precursor is an active ester of 3-fluoro-5-radioiodotyrosine which can be coupled to a compound including an amino group to produce a monoradioiodinated derivative of the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.