Patent · US Expired

Monoradioiodinated imidazole derivatives

US4310675A · kind A · utility

2Cited by
0References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 24, 1979
Grant dateJan 12, 1982
Priority date
Expiry dateMay 24, 1999

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N33/60
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Monoradioiodinated derivatives of compounds employed in a radioassay prepared from precursors which are either active esters, amino acids, or amines, including a phenolic of imidazole substituent group in which one of the possible two sites on the group for radioiodination is substituted to permit production of a monoradioiodinated derivative. A preferred precursor is an active ester of 3-fluoro-5-radioiodotyrosine which can be coupled to a compound including an amino group to produce a monoradioiodinated derivative of the compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.