Therapeutically active derivatives of benzamide
US4312862A · kind A · utility
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Key dates
| Filing date | Jul 19, 1979 |
| Grant date | Jan 26, 1982 |
| Priority date | — |
| Expiry date | Jul 19, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C311/39
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel therapeutically active derivatives of benzamide, having the general formula ##STR1## in which R.sub.1 and R.sub.2, independently of each other, are hydrogen or a lower alkyl group, R.sub.3 is a phenyl or lower alkyl or lower alkenyl group, R.sub.4 is a halogen or a trifluoromethyl or nitro-group, R.sub.5 is a sulphamoyl or carboxyl or carboxy-alkyl group, and the potassium salts of these derivatives. These compounds are diuretics and hypotensors (blood pressure depressants) and they lower the angiotensin and renin functions, with prolonged action.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.