Monosubstituted piperazines
US4312869A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 11, 1980 |
| Grant date | Jan 26, 1982 |
| Priority date | — |
| Expiry date | Sep 11, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/42
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Biphenylalkylene-thiazolyl-piperazines of the formula ##STR1## wherein Ar and A are as defined herein, e.g., 1-[4-(4-phenylsulfinylbenzyl)-2-thiazolyl]piperazine, and 1-[4-(4-biphenylylmethyl)-2-thiazolyl]piperazine, and their physiologically tolerable salts are provided. These compounds are useful as medicines for the treatment of inflammation with an immunological component, and are useful as hypolipemic and hypocholesterolemic agents and to assist lowering of lipid and cholesterol content in the blood.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.