Patent · US Expired

Monosubstituted piperazines

US4312869A · kind A · utility

0Cited by
1References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 11, 1980
Grant dateJan 26, 1982
Priority date
Expiry dateSep 11, 2000

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D277/42
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Biphenylalkylene-thiazolyl-piperazines of the formula ##STR1## wherein Ar and A are as defined herein, e.g., 1-[4-(4-phenylsulfinylbenzyl)-2-thiazolyl]piperazine, and 1-[4-(4-biphenylylmethyl)-2-thiazolyl]piperazine, and their physiologically tolerable salts are provided. These compounds are useful as medicines for the treatment of inflammation with an immunological component, and are useful as hypolipemic and hypocholesterolemic agents and to assist lowering of lipid and cholesterol content in the blood.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.