Furocoumarin for the photochemotherapy of psoriasis and related skin diseases
US4312883A · kind A · utility
32Cited by
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11Claims
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Key dates
| Filing date | Aug 15, 1980 |
| Grant date | Jan 26, 1982 |
| Priority date | — |
| Expiry date | Aug 15, 2000 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A class of alkyl-substituted angular flurocoumarins, sometimes termed alkylangelicins, useful in the photochemotherapy of psoriasis and in other skin diseases characterized by cellular hyperproliferation or lack of skin pigmentation is disclosed for topical application or systemic administration. Compared with conventional psoralens the described compounds exhibit a lower risk of skin cancer, absence of phototoxicity problems anderithema to the patient so treated. One preferred compound is 5-methylangelicin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.