Chemotherapeutically active maytansinoids from Trewia nudiflora
US4313946A · kind A · utility
292Cited by
2References
8Claims
0Family size
Assignee
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Key dates
| Filing date | Jan 27, 1981 |
| Grant date | Feb 2, 1982 |
| Priority date | — |
| Expiry date | Jan 27, 2001 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel group of maytansinoid compounds has been discovered in the seed tissue of Trewia nudiflora. They are represented by the general formula ##STR1## and are all characterized by a distinguishing methoxy group on the C-15 carbon. These isolates have proven to be effective in causing the remission of one or more types of malignancies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.