Patent · US Expired

3'-Deamino-3'-(4-methoxy-1-piperidinyl) derivatives of daunorubicin and doxorubicin

US4314054A · kind A · utility

9Cited by
4References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 23, 1981
Grant dateFeb 2, 1982
Priority date—
Expiry dateMar 23, 2001

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H15/252
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Described are 3'-deamino-3'-(4-methoxy-1-piperidinyl) derivatives of daunorubicin and doxorubicin having the formula ##STR1## wherein R is COCH.sub.3 or --CHOHCH.sub.3 in the case of daunorubicin derivatives, or is COCH.sub.2 OH or --CHOH--CH.sub.2 OH in the case of doxorubicin derivatives together with their pharmaceutically acceptable acid salts. The compounds have utility as antitumor agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.