Folic acid derivatives and process for preparation
US4314988A · kind A · utility
14Cited by
7References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 31, 1979 |
| Grant date | Feb 9, 1982 |
| Priority date | — |
| Expiry date | Oct 31, 1999 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/82
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Folic acid derivatives, such as radiolabeled pteroyltyrosine, are conveniently synthesized from either pteroic acid or by the direct condensation of 6-formylpterin with p-aminobenzoyltyrosine methyl ester. The radioiodinated derivatives are particularly useful in competitive protein binding and radioimmuno-assays of folate compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.