4-Amino-6,7-dimethoxyquinazol-2-yl alkylenediamines
US4315007A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Dec 10, 1979 |
| Grant date | Feb 9, 1982 |
| Priority date | — |
| Expiry date | Dec 10, 1999 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D307/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Alkylenediamine amides corresponding to the general formula (I) ##STR1## in which R.sub.1 and R.sub.2 each represent, independently of one another, a hydrogen atom, an alkyl having 1 to 4 carbon atoms or the benzyl radical, n is equal to 2, 3 or 4 and R represents either a cycloalkyl radical having 3 to 6 carbon atoms, or a radical ##STR2## in which m is 0, 1 or 2, ##STR3## in which m is 0, 1 or 2 and p is 0, 1 or 2, and also their addition salts with pharmaceutically acceptable acids. These compounds may be prepared by reacting an aminoamide ##STR4## with a 4-amino-2-halogeno-6,7-dimethoxyquinazoline (II). The compounds are useful in treating cardiovascular disorders, and pharmaceutical compositions containing the compounds are also claimed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.