Benzo-as-triazine derivatives
US4316022A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 28, 1980 |
| Grant date | Feb 16, 1982 |
| Priority date | — |
| Expiry date | Mar 28, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to new benzo-as-triazine derivatives of the formulae (I) and (Ia) and pharmaceutically acceptable acid addition salts thereof, ##STR1## wherein R.sub.1 and R.sub.2 each represent hydrogen, a C.sub.1-20 alkylcarbonyl group, a phenylcarbonyl or phenyl-(C.sub.1-4 alkyl)-carbonyl group having optionally one or more halogen, hydroxy or C.sub.1-3 alkoxy substituents which may be the same or different, furthermore a pyridylcarbonyl, a pyrazinylcarbonyl, a furylcarbonyl, a chloroacetyl or a C.sub.1-4 alkoxycarbonyl group, or PA1 R.sub.1 and R.sub.2 may form, together with the adjacent nitrogen atoms, a pyrazole ring having optionally a C.sub.1-6 alkyl substituent in position 4, with the proviso that one of R.sub.1 and R.sub.2 is always different from hydrogen, PA1 R.sub.3 stands for hydrogen, mercapto group, a C.sub.1-4 alkylmercapto group, amino group, a C.sub.1-4 alkylamino group, a piperazino group having optionally an N-alkyl or 2-pyridyl substituent, a morpholino group or a piperidino group, and PA1 R.sub.4 stands for hydrogen, halogen, C.sub.1-4 alkyl or C.sub.1-4 alkoxy group. The compounds of the formulae (I) and (Ia) are prepared by acylating the respective 2…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.