Patent · US Expired

[(5,6,9a-Substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)oxy]alka noic and cycloalkanoic acids and their analogs, esters, salts and derivatives

US4316043A · kind A · utility

39Cited by
9References
32Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 19, 1980
Grant dateFeb 16, 1982
Priority date
Expiry dateDec 19, 2000

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2603/18
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to novel [(5,6,9a-substituted-3-oxo-1,2,9,9a-tetrahydro-3H-fluoren-7-yl)-oxy]alkano ic and cycloalkanoic acids and their analogs, esters, salts and derivatives. These compounds are synthesized by methods selected from a number of synthetic routes depending on the particular structure, choice of intermediate or preferred reaction sequence. The compounds are useful in the treatment and prevention of injury to the brain and spinal chord due to accidents, ischemic stroke and hydrocephalus; compositions for such uses are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.