Patent · US Expired

Process for the purification of ursodeoxycholic acid

US4316848A · kind A · utility

1Cited by
3References
5Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 11, 1980
Grant dateFeb 23, 1982
Priority date
Expiry dateJul 11, 2000

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07J51/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A mixture of ursodeoxycholic acid and of chenodeoxycholic acid as well as of their salts and esters is reacted with a silylating agent in a suitable anhydrous organic solvent; the corresponding silyl-derivatives thus obtained are separated by crystallization and pure ursodeoxycholic acid is recovered from the corresponding silyl-derivatives in the usual manner.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.