Extended N-terminal somatostatin
US4316891A · kind A · utility
64Cited by
5References
6Claims
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Key dates
| Filing date | Jun 14, 1980 |
| Grant date | Feb 23, 1982 |
| Priority date | — |
| Expiry date | Jun 14, 2000 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
28-member residue and 25-member residue peptides have been synthesized containing the tetradecapeptide somatostatin that are more potent than somatostatin. Somatostatin-28 has the formula: ##STR1## The three N-terminal amino acid residues are absent in somatostatin-25. Somatostatin-28 or somatostatin-25 or a pharmaceutically acceptable addition salt thereof, dispersed in a pharmaceutically acceptable liquid or solid carrier, can be administered to mammals in the same manner as somatostatin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.