Patent · US Expired

Muramyldipeptide derivatives

US4317771A · kind A · utility

20Cited by
1References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 23, 1980
Grant dateMar 2, 1982
Priority date
Expiry dateJun 23, 2000

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P31/04
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Muramyldipeptide derivatives of the formula (I): ##STR1## wherein X represents an amino acid residue such as of L-alanine, L-serine, L-valine, glycine, etc., and Y represents a group ##STR2## wherein R.sub.1 represents a hydrogen atom, an alkyl group of 1 to 6 carbon atoms, a carboxamide group or a carboxyl group, n represents an integer of 1 to 6, A represents a straight or branched chain, saturated or unsaturated aliphatic hydrocarbon residue of 7 to 30 carbon atoms, and "Acyl" means an acyl group of an aliphatic carboxylic acid having 2 to 6 carbon atoms. These compounds have excellent adjuvant activity and/or prophylactic and therapeutic effects against microbial infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.