Technetium-99m-labelled (2,4,5-trimethylacetanilido)-iminodiacetate for liver function diagnosis, chloroacetric acid (2,4,5-trimethylanilide), (2,4,5-trimethylacetanilido)-iminodiacetate, and process for their preparation

US4318898A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Michael Molter · Dunlap, US
• Gerhard Kloss · Kelkheim, DE
• Eberhard Schickel · Bad Camberg, DE

Key dates

• Filing date: Dec 19, 1979
• Grant date: Mar 9, 1982
• Expiry date: Dec 19, 1999

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2123/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

What are disclosed are a diagnostic agent for visualizing the hepatobiliary system which agent contains Technetium-99m-labelled (2,4,5-trimethylacetanilido)-iminodiacetate in a suitable solvent, and a process for the preparation of this diagnostic agent; chloroacetic acid-(2,4,5-trimethylanilide) as an intermediate product and a process for the preparation thereof; and (2,4,5-trimethylacetanilido)-iminodiacetate and a process for the preparation thereof.