Separation of proteases from fluids
US4318990A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 15, 1980 |
| Grant date | Mar 9, 1982 |
| Priority date | — |
| Expiry date | May 15, 2000 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/815
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Proteases are separated from fluids by contacting a fluid with a porous inorganic material such as porous titania particles to sorb the protease and then eluting the protease from the inorganic material. Proteases which may be separated are the sulphydryl proteases including papain, stem bromelain, fruit bromelain, ficin, calotropain and mexicain. Elution of the protease may be carried out with plant juice from which protease has previously been removed. The porous inorganic material is preferably that prepared by mixing a finely divided sorptive inorganic material with a solid fugitive additive and a solvent to dissolve the fugitive, forming discrete particles from the resultant mixture and heating the particles to remove the solvent and fugitive to produce discrete particles of the inorganic material for contacting with the fluid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.