Preparation of 1,3-dibromo-2,2-dimethyl-propane-1,3-dicarboxylic acid derivatives

US4321408A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Fritz Maurer · Wuppertal, DE
• Uwe Priesnitz · Solingen, DE
• Hans-Jochem Riebel · Bad Camberg, DE

Key dates

• Filing date: May 27, 1980
• Grant date: Mar 23, 1982
• Expiry date: May 27, 2000

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C55/40
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

In the preparation of a 1,3-dibromo-2,2-dimethyl-propane-1,3-dicarboxylic acid derivative of the formula ##STR1## in which R.sup.1 and R.sup.2 each independently is chlorine or alkoxy, by reacting a 2,2-dimethyl-propane-1,3-dicarboxylic acid derivative of the formula ##STR2## in which R.sup.3 is hydroxy or alkoxy and PA0 R.sup.4 is hydroxy, or PA0 R.sup.3 and R.sup.4 together are an anhydride oxygen atom, with an acid halide, then reacting the product with bromine at a temperature between 0.degree. and 150.degree. C. to form a 1,3-dibromo-2,2-dimethyl-propane-1,3-dicarboxylic acid chloride and optionally reacting such acid chloride with an alkanol, the improvement which comprises employing an acid chloride as the acid halide, e.g. phosphorus pentachloride, phosphorus oxychloride, phosphorus trichloride, thionyl chloride or phosgene. Compounds of the formula ##STR3## are new. The products are intermediates for making insecticides.