Patent · US Expired

Triazole acylamines, pharmaceutical compositions thereof and method of use thereof

US4323566A · kind A · utility

9Cited by
4References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 29, 1980
Grant dateApr 6, 1982
Priority date
Expiry dateFeb 29, 2000

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D333/36
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts, hydrates and bioprecursors thereof, in which PA0 R.sub.1 and R.sub.2, which may be the same of different, each represent hydrogen, C.sub.1 alkyl, cycloalkyl, alkenyl, alkynyl, aralkyl, trifluoroalkyl, or alkyl substituted by hydroxy, alkoxy, amino alkylamino dialkylamino or cycloalkyl or R.sub.1 and R.sub.2 may together with the nitrogen atom to which they are attached form a 5 to 10 membered ring which may be saturated or may contain at least one double bond, may be unsubstituted or may be substituted by one or more C.sub.1-3 alkyl groups or a hydroxy group and/or may contain another heteroatom which is oxygen or sulphur; PA0 Alk represents a straight or branched alkylene chain of 1 to 6 carbon atoms, PA0 Q represents a furan or thiophene ring in which incorporation into the rest of the molecule is through bonds at the 2- and 5- positions, the furan ring optionally bearing a further substituent R.sub.6 adjacent to the group R.sub.1 R.sub.2 N-Alk, or Q represents a benzene ring in which incorporation into the rest of the molecule is through bonds at the 1- and 3- or 1- and 4…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.