Chiral supports for resolution of racemates
US4324681A · kind A · utility
24Cited by
2References
9Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 12, 1980 |
| Grant date | Apr 13, 1982 |
| Priority date | — |
| Expiry date | Jun 12, 2000 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2998
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A silylated silica or alumina covalently bonded to a chiral amino acid through a carboxyl group of said acid may be used as the solid stationary phase in the chromatographic resolution of racemic mixtures. Several classes of derivatives of such bound chiral amino acids also may be used in the resolution of racemates. Such derivatives include N-alkyl and N-acyl derivatives, and esters where the amino acid is a dicarboxylic acid or contains a hydroxy group.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.