4-Aryl-4-aryloxypiperidines
US4325953A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Sep 3, 1980 |
| Grant date | Apr 20, 1982 |
| Priority date | — |
| Expiry date | Sep 3, 2000 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/32
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
4-Aryl-4-aryloxypiperidines of the general formula (I) ##STR1## and their pharmaceutically acceptable acid addition salts, wherein R.sup.1 and R.sup.2 are hydrogen or lower alkyl, R.sup.3 is hydrogen, lower alkyl or benzyl, Ar is phenyl optionally substituted by one or more halogen, trifluoromethyl, lower alkyl, lower alkoxy, nitro or amino groups and Ar.sup.1 is a phenyl radical optionally substituted by one or more cyano, methylsulphinyl, methylsulphonyl, lower alkoxy, trifluoromethyl, lower alkyl, lower alkenyl, halogen, nitro, amino or acylamino groups or an aromatic heterocyclic mono- or di-cyclic radical, exhibit activity on the central nervous system, e.g. as antidepressants.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.